Medicamentul care ar putea trata cancerul la sân

Un medicament utilizat pentru tratarea carcinomului pulmonar, altul decât cel cu celule mici, poate sta la baza unei noi terapii ţintite pentru miile de paciente diagnosticate cu cancer mamar, conform concluziilor unui studiu citat luni de Press Association.

Oamenii de ştiinţă din cadrul Institutului pentru Cercetarea Cancerului din Marea Britanie au descoperit că medicamentul crizotinib, folosit în prezent contra tumorilor pulmonare, poate distruge celulele canceroase care prezintă o anumită mutaţie genetică, scrie Agerpres.

În urma studiilor, ei au concluzionat că acesta poate ţinti carcinomul lobular invaziv ce prezintă mutaţia e-caderină pe baza unei abordări terapeutice cunoscută sub denumirea de letalitate sintetică.

Potrivit estimărilor, doar în Marea Britanie circa 7.150 de femei sunt diagnosticate anual cu tumori de sân care prezintă această mutaţie genetică. Însă, în ciuda prevalenţei crescute, nu există în prezent niciun tratament care ţinteşte în mod specific acest tip de celule canceroase despre care sunt cunoscute foarte puţine lucruri.

Oamenii de ştiinţă notează că în cazul celulelor normale, proteina e-caderină acţionează ca un liant, ajutându-le să se unească, însă mutaţiile la nivelul e-caderinei cauzează dezvoltarea celulelor canceroase şi diviziunea lor anormală.

Etichete: medicamentcancer la sanmedicamentul pentru tratarea cancerului



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